CHEK1 anticorps (pSer345)

N° du produit ABIN232760

L’anticorps Lapin Polyclonal anti-CHEK1 a été validé pour WB. Il convient pour détecter CHEK1 dans des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour CHEK1 anticorps (pSer345) (ABIN232760)

Antigène: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHEK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CHEK1 anticorps

Épitope: pSer345

Specificité: Detects endogenous levels of Chk1 only when activated by phosphorylation at serine 345. Does not recognize Chk1 phosphorylated at other sites. Species cross-reactivity: Monkey, mouse and rat.

Purification: Protein A purified

Immunogène: Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser345 of human Chk1.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: WB (1:1000)

Usage: Western Blot: 1:1000, incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4?C with gentle shaking, overnight. Flow Cytometry: 1:50.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur CHEK1

Antigène: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Autre désignation: CHEK1 / CHK1

Sujet: Name/Gene ID: CHEK1
Subfamily: NIM1
Family: Protein Kinase

Synonyms: CHEK1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase 1, CHK1, Chk1-S, Protein kinase chk1, Checkpoint kinase-1

ID gène: 1111

UniProt: O14757

Pathways: Signalisation p53, Apoptose, Cycle Cellulaire, Réparation de l'ADN